BDBM8676 2-{4-[(2E)-2-(pyridin-4-ylmethylidene)hydrazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}-1,3-thiazole::pyrazolopyrimidine derivative 28

SMILES C(N=Nc1ncnc2n(ncc12)-c1nccs1)c1ccncc1

InChI Key InChIKey=XCJMZJIFUIXYOR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8676   

TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8676(2-{4-[(2E)-2-(pyridin-4-ylmethylidene)hydrazin-1-y...)
Affinity DataIC50: 39.8nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed