BDBM8710 4-[(1E)-1-{2-[1-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]hydrazin-1-ylidene}ethyl]pyridine::pyrazolopyrimidine derivative 62

SMILES COc1cccc(c1)-n1ncc2c(N=NC(C)c3ccncc3)ncnc12

InChI Key InChIKey=RCDPINCYPCBQQS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8710   

TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8710(4-[(1E)-1-{2-[1-(3-methoxyphenyl)-1H-pyrazolo[3,4-...)
Affinity DataIC50: 63.1nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed