BDBM8723 6-Amino-N-methyl-N-(1-methyl-1H-indol-2-yl)nicotinamide::6-amino-N-methyl-N-[(1-methyl-1H-indol-2-yl)methyl]pyridine-3-carboxamide::aminopyridine deriv. 12

SMILES CN(Cc1cc2ccccc2n1C)C(=O)c1ccc(N)nc1

InChI Key InChIKey=WUAULDNTPAVINA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8723   

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
Glaxosmithkline

LigandPNGBDBM8723(6-amino-N-methyl-N-[(1-methyl-1H-indol-2-yl)methyl...)
Affinity DataIC50: 1.00E+5nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2006
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Glaxosmithkline

LigandPNGBDBM8723(6-amino-N-methyl-N-[(1-methyl-1H-indol-2-yl)methyl...)
Affinity DataIC50: 1.92E+4nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2006
Entry Details Article
PubMed