BDBM8761 1,2,3,4-Tetrahydropyrido[3,4-b]indole 6::4-{1H,2H,3H,4H,9H-pyrido[3,4-b]indol-2-ylcarbonyl}phenol

SMILES Oc1ccc(cc1)C(=O)N1CCc2c(C1)[nH]c1ccccc21

InChI Key InChIKey=KEBXFLCCYVJERH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8761   

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
Glaxosmithkline

LigandPNGBDBM8761(4-{1H,2H,3H,4H,9H-pyrido[3,4-b]indol-2-ylcarbonyl}...)
Affinity DataIC50: 1.40E+3nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2006
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
Glaxosmithkline

LigandPNGBDBM8761(4-{1H,2H,3H,4H,9H-pyrido[3,4-b]indol-2-ylcarbonyl}...)
Affinity DataIC50: 1.80E+4nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2006
Entry Details Article
PubMed