BDBM8762 1,2,3,4-Tetrahydropyrido[3,4-b]indole 7::4-({9-methyl-1H,2H,3H,4H,9H-pyrido[3,4-b]indol-2-yl}carbonyl)phenol

SMILES Cn1c2CN(CCc2c2ccccc12)C(=O)c1ccc(O)cc1

InChI Key InChIKey=HULPDUSLVKXARL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8762   

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
Glaxosmithkline

LigandPNGBDBM8762(4-({9-methyl-1H,2H,3H,4H,9H-pyrido[3,4-b]indol-2-y...)
Affinity DataIC50: 1.40E+3nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2006
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
Glaxosmithkline

LigandPNGBDBM8762(4-({9-methyl-1H,2H,3H,4H,9H-pyrido[3,4-b]indol-2-y...)
Affinity DataIC50: 1.10E+4nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2006
Entry Details Article
PubMed