BDBM8764 1,2,3,4-Tetrahydropyrido[3,4-b]indole 9::methyl 5-{2-[(4-hydroxyphenyl)carbonyl]-1H,2H,3H,4H,9H-pyrido[3,4-b]indol-9-yl}pentanoate

SMILES COC(=O)CCCCn1c2CN(CCc2c2ccccc12)C(=O)c1ccc(O)cc1

InChI Key InChIKey=UOKCHPKAWHMZFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8764   

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
Glaxosmithkline

LigandPNGBDBM8764(methyl 5-{2-[(4-hydroxyphenyl)carbonyl]-1H,2H,3H,4...)
Affinity DataIC50: 4.60E+3nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2006
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
Glaxosmithkline

LigandPNGBDBM8764(methyl 5-{2-[(4-hydroxyphenyl)carbonyl]-1H,2H,3H,4...)
Affinity DataIC50: 2.68E+4nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2006
Entry Details Article
PubMed