BDBM8782 1,2,3,4-tetrahydro pyrido[3,4-b]indole 26::4-[(2-{[4-(methylamino)phenyl]carbonyl}-1H,2H,3H,4H,9H-pyrido[3,4-b]indol-9-yl)methyl]phenol

SMILES CNc1ccc(cc1)C(=O)N1CCc2c(C1)n(Cc1ccc(O)cc1)c1ccccc21

InChI Key InChIKey=QRVFCDZIXUSSOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8782   

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
Glaxosmithkline

LigandPNGBDBM8782(4-[(2-{[4-(methylamino)phenyl]carbonyl}-1H,2H,3H,4...)
Affinity DataIC50: 2.10E+3nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2006
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
Glaxosmithkline

LigandPNGBDBM8782(4-[(2-{[4-(methylamino)phenyl]carbonyl}-1H,2H,3H,4...)
Affinity DataIC50: 3.86E+4nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2006
Entry Details Article
PubMed