BDBM8789 1,2,3,4-tetrahydro pyrido[3,4-b]indole 33::2-chloro-4-({9-[(4-hydroxyphenyl)methyl]-1H,2H,3H,4H,9H-pyrido[3,4-b]indol-2-yl}carbonyl)phenol

SMILES Oc1ccc(Cn2c3CN(CCc3c3ccccc23)C(=O)c2ccc(O)c(Cl)c2)cc1

InChI Key InChIKey=OZJBQBSQGZHHNA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8789   

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
Glaxosmithkline

LigandPNGBDBM8789(2-chloro-4-({9-[(4-hydroxyphenyl)methyl]-1H,2H,3H,...)
Affinity DataIC50: 160nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2006
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
Glaxosmithkline

LigandPNGBDBM8789(2-chloro-4-({9-[(4-hydroxyphenyl)methyl]-1H,2H,3H,...)
Affinity DataIC50: 3.40E+3nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2006
Entry Details Article
PubMed