BDBM8831 3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(2-methoxyphenyl)urea::N-[4-(4-Amino-6-methylthieno[2,3-d]pyrimidin-5-yl)-phenyl]-N -(2-methoxyphenyl)urea::Thienopyrimidine deriv. 13

SMILES COc1ccccc1NC(=O)Nc1ccc(cc1)-c1c(C)sc2ncnc(N)c12

InChI Key InChIKey=GWKIGGBPQCNPSU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 8831   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8831(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 110nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8831(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 50nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

LigandPNGBDBM8831(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 920nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8831(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 50nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8831(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 50.1nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8831(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 110nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

LigandPNGBDBM8831(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 912nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed