BDBM8866 3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-chlorophenyl)-1-(3-methylphenyl)urea::N-[4-(4-Aminothieno[2,3-d]pyrimidin-5-yl)-2-chlorophenyl]-N -(3-methylphenyl)urea::Thienopyrimidine deriv. 92

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2Cl)-c2csc3ncnc(N)c23)c1

InChI Key InChIKey=HWUKVYPOCLJTSN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 8866   

TargetAromatase(Human)
Abbott Laboratories

LigandPNGBDBM8866(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-chloro...)
Affinity DataIC50: 700nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8866(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-chloro...)
Affinity DataIC50: 83nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8866(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-chloro...)
Affinity DataIC50: 54nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8866(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-chloro...)
Affinity DataIC50: 54nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8866(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-chloro...)
Affinity DataIC50: 83.2nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8866(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-chloro...)
Affinity DataIC50: 53.7nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed