BDBM8868 3-{16-amino-11-thia-13,15-diazatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-1(10),2(7),3,5,12,14,16-heptaen-5-yl}-1-(3-methylphenyl)urea::N-(11-Amino-5,6-dihydro-7-thia-8,10-diazabenzo[c]-fluoren-3-yl)-N -(3-methylphenyl)urea::Thienopyrimidine deriv. 94

SMILES Cc1cccc(NC(=O)Nc2ccc3-c4c(CCc3c2)sc2ncnc(N)c42)c1

InChI Key InChIKey=XLFYOIVELARSKP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8868   

TargetAromatase(Human)
Abbott Laboratories

LigandPNGBDBM8868(3-{16-amino-11-thia-13,15-diazatetracyclo[8.7.0.0^...)
Affinity DataIC50: 36nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8868(3-{16-amino-11-thia-13,15-diazatetracyclo[8.7.0.0^...)
Affinity DataIC50: 150nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8868(3-{16-amino-11-thia-13,15-diazatetracyclo[8.7.0.0^...)
Affinity DataIC50: 151nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed