BDBM8869 3-(4-{4-amino-6-ethylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-[3-(trifluoromethyl)phenyl]urea::N-[4-(4-Amino-6-ethylthieno[2,3-d]pyrimidin-5-yl)-phenyl]-N -[3-(trifluoromethyl)phenyl]urea::Thienopyrimidine deriv. 95

SMILES CCc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=RRDYFNCNBSDAMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8869   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8869(3-(4-{4-amino-6-ethylthieno[2,3-d]pyrimidin-5-yl}p...)
Affinity DataIC50: 50nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8869(3-(4-{4-amino-6-ethylthieno[2,3-d]pyrimidin-5-yl}p...)
Affinity DataIC50: 50.1nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed