BDBM8980 N-[(1-benzylpiperidin-4-yl)methyl]-2-(1,2,3,4-tetrahydroacridin-9-ylamino)acetamide::tacrine-E2020 analog 4

SMILES O=C(CNc1c2CCCCc2nc2ccccc12)NCC1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=FFAKLQUDTIUSJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8980   

TargetAcetylcholinesterase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM8980(N-[(1-benzylpiperidin-4-yl)methyl]-2-(1,2,3,4-tetr...)
Affinity DataIC50: 10.2nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM8980(N-[(1-benzylpiperidin-4-yl)methyl]-2-(1,2,3,4-tetr...)
Affinity DataIC50: 12.4nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed