BDBM92653 C7-substituted chromone derivative, 3d

SMILES Clc1cccc(COc2ccc3c(c2)occc3=O)c1

InChI Key InChIKey=ZATAXWRTJHAXCN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 92653   

TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM92653(C7-substituted chromone derivative, 3d)
Affinity DataIC50: 1.52E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition studies using recombinant human MAO-A and MAO-B that were obtained from commercial sources (Sigma-Aldrich).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM92653(C7-substituted chromone derivative, 3d)
Affinity DataIC50: 17nMpH: 7.4 T: 2°CAssay Description:Inhibition studies using recombinant human MAO-A and MAO-B that were obtained from commercial sources (Sigma-Aldrich).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM92653(C7-substituted chromone derivative, 3d)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in insect cell microsomes using kynuramine as substrate assessed as decrease in 4-hydroxyquinoline pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM92653(C7-substituted chromone derivative, 3d)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM92653(C7-substituted chromone derivative, 3d)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM92653(C7-substituted chromone derivative, 3d)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human MAO-B expressed in insect cell microsomes using kynuramine as substrate assessed as decrease in 4-hydroxyquinoline pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed