BDBM93207 Kinase inhibitor, 5

SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1ccc2nc(Nc3ccc(OCCN)cc3)ncc2c1

InChI Key InChIKey=PVCFUSCWDDWVIQ-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 93207   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

LigandPNGBDBM93207(Kinase inhibitor, 5)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Fluorescence assay used for determination of catch and release efficiency. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Washington

LigandPNGBDBM93207(Kinase inhibitor, 5)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Fluorescence assay used for determination of catch and release efficiency. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
University of Washington

LigandPNGBDBM93207(Kinase inhibitor, 5)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Fluorescence assay used for determination of catch and release efficiency. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Washington

LigandPNGBDBM93207(Kinase inhibitor, 5)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Fluorescence assay used for determination of catch and release efficiency. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Washington

LigandPNGBDBM93207(Kinase inhibitor, 5)
Affinity DataIC50: 8.40nMpH: 7.5 T: 2°CAssay Description:Fluorescence assay used for determination of catch and release efficiency. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 10(Human)
University of Washington

LigandPNGBDBM93207(Kinase inhibitor, 5)
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:Fluorescence assay used for determination of catch and release efficiency. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 10(Human)
University of Washington

LigandPNGBDBM93207(Kinase inhibitor, 5)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:Fluorescence assay used for determination of catch and release efficiency. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
University of Washington

LigandPNGBDBM93207(Kinase inhibitor, 5)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:Fluorescence assay used for determination of catch and release efficiency. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
University of Washington

LigandPNGBDBM93207(Kinase inhibitor, 5)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescence assay used for determination of catch and release efficiency. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
University of Washington

LigandPNGBDBM93207(Kinase inhibitor, 5)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescence assay used for determination of catch and release efficiency. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 5(Human)
University of Washington

LigandPNGBDBM93207(Kinase inhibitor, 5)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescence assay used for determination of catch and release efficiency. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
University of Washington

LigandPNGBDBM93207(Kinase inhibitor, 5)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescence assay used for determination of catch and release efficiency. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed