BDBM9614 2-[(2R,3S)-3-[(2S)-3-(benzylsulfanyl)-2-acetamidopropanamido]-2-hydroxy-4-phenylbutyl]-N-tert-butylbenzamide::D-Cysteine Analog 13a

SMILES CC(=O)N[C@H](CSCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)Cc1ccccc1C(=O)NC(C)(C)C

InChI Key InChIKey=VMNCMSQBCKDMCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 9614   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM9614(2-[(2R,3S)-3-[(2S)-3-(benzylsulfanyl)-2-acetamidop...)
Affinity DataIC50: 45nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2006
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM9614(2-[(2R,3S)-3-[(2S)-3-(benzylsulfanyl)-2-acetamidop...)
Affinity DataIC50: 1.00E+3nMAssay Description:Concentration required for in vitro inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article