BDBM9627 (S)-N-(1S,2R)-[3-[2-[[(1,1-Dimethylethyl)amino]]carbonyl]phenyl]-2-hydroxy-1-(phenylmethyl)-propyl]-2-[(methylsulfonyl)amino]-3-(2-pyridylthio)propanamide::D-Cysteine Analog 16f::N-tert-butyl-2-[(2R,3S)-2-hydroxy-3-[(2S)-2-methanesulfonamido-3-(pyridin-2-ylsulfanyl)propanamido]-4-phenylbutyl]benzamide

SMILES CC(C)(C)NC(=O)c1ccccc1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CSc1ccccn1)NS(C)(=O)=O

InChI Key InChIKey=PYGQGWQNWPDXOO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9627   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM9627((S)-N-(1S,2R)-[3-[2-[[(1,1-Dimethylethyl)amino]]ca...)
Affinity DataIC50: 910nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2006
Entry Details Article
PubMed