BDBM9630 (S)-N-(1S,2R)-[3-[2-[[(1,1-Dimethylethyl)amino]carbonyl]phenyl]-2-hydroxy-1-(phenylmethyl)-propyl]-2-[(methylsulfonyl)amino]-3-[(1-N-methyltetrazol-5-yl)thio]propanamide::D-Cysteine Analog 16i::N-tert-butyl-2-[(2R,3S)-2-hydroxy-3-[(2S)-2-methanesulfonamido-3-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]propanamido]-4-phenylbutyl]benzamide

SMILES Cn1nnnc1SC[C@@H](NS(C)(=O)=O)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)Cc1ccccc1C(=O)NC(C)(C)C

InChI Key InChIKey=LRPLMBCLVHSVQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9630   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM9630(N-tert-butyl-2-[(2R,3S)-2-hydroxy-3-[(2S)-2-methan...)
Affinity DataIC50: 17.5nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2006
Entry Details Article
PubMed