BDBM9732 P3-capped alpha-ketoamide inhibitor 48::tert-butyl N-[(1S)-2-[(2S)-2-[(1-{[(benzylcarbamoyl)methyl]carbamoyl}-1-oxopentan-2-yl)carbamoyl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]carbamate

SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)NCc1ccccc1

InChI Key InChIKey=DXBIMOUGPNBXPJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9732   

TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM9732(tert-butyl N-[(1S)-2-[(2S)-2-[(1-{[(benzylcarbamoy...)
Affinity DataKi:  4.50E+4nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2006
Entry Details Article
PubMed