BDBM9734 2-oxoimidazolidine-4-carboxylic acid deriv. 7::tert-butyl (4S)-4-{[(1S)-4-(tert-butoxy)-1-{[(1S)-2-methyl-1-{[(2S)-3-methyl-1-oxo-1-[(5S)-2-oxo-5-{[1-oxo-1-(prop-2-en-1-ylcarbamoyl)pentan-2-yl]carbamoyl}imidazolidin-1-yl]butan-2-yl]carbamoyl}propyl]carbamoyl}-4-oxobutyl]carbamoyl}-4-acetamidobutanoate

SMILES CCCC(NC(=O)[C@@H]1CNC(=O)N1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(C)=O)C(C)C)C(C)C)C(=O)C(=O)NCC=C

InChI Key InChIKey=XAIWSWDAFZANQU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9734   

TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM9734(tert-butyl (4S)-4-{[(1S)-4-(tert-butoxy)-1-{[(1S)-...)
Affinity DataKi:  6.90E+4nM ΔG°:  -5.77kcal/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2006
Entry Details Article
PubMed