BDBM98032 US8486953, 2

SMILES CCOc1cc(ccc1Nc1ncnc2sc(C(N)=O)c(C)c12)C(N)=O

InChI Key InChIKey=DGUSKGFGXIHXKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 98032   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM98032(US8486953, 2)
Affinity DataIC50: 120nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM98032(US8486953, 2)
Affinity DataIC50: 28nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
Go to US Patent