BDBM98526 US8481733, 338

SMILES CC(=O)Nc1cc(ccc1Oc1ccccc1)-c1nc(C2CCC2)n2ccnc(N)c12

InChI Key InChIKey=JLFUKRVOPOHPCN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 98526   

TargetActivated CDC42 kinase 1(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM98526(US8481733, 338)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ACK1 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM98526(US8481733, 338)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds of the invention were tested for ACK1 inhibition activity. 1 uL compounds prepared at 15× in 4 mM DMSO were combined with 9 uL ATP so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2013
Entry Details
US Patent