BDBM98608 2-amino-1-ethyl-7-[2-(1-hydroxycyclobutyl)ethynyl]-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide::US8470847, 12

SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC1(O)CCC1

InChI Key InChIKey=NOSCHXKCZVKDRR-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98608   

TargetVascular endothelial growth factor receptor 3(Human)
Sanofi

US Patent

LigandBDBM98608(2-amino-1-ethyl-7-[2-(1-hydroxycyclobutyl)ethynyl]...)Copy SMILESCopy InChI

Affinity DataIC50: 21nMT: 2°CAssay Description:Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/29/2013
Entry Details
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