BDBM98611 2-amino-7-(3,4-dihydroxy-3-methyl-but-1-ynyl)-N-methyl-4-oxo-1-tetrahydropyran-4-yl-1,8-naphthyridine-3-carboxamide::US8470847, 37

SMILES CNC(=O)c1c(N)n(C2CCOCC2)c2nc(ccc2c1=O)C#CC(C)(O)COC

InChI Key InChIKey=USNWADHMHCNMLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98611   

LigandPNGBDBM98611(2-amino-7-(3,4-dihydroxy-3-methyl-but-1-ynyl)-N-me...)
Affinity DataIC50: 34nMT: 2°CAssay Description:Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
Go to US Patent