BDBM98612 2-amino-7-(3-hydroxy-3-methyl-but-1-ynyl)-N-methyl-4-oxo-1-(tetrahydrofuran-2-ylmethyl)-1,8-naphthyridine-3-carboxamide::US8470847, 46

SMILES CNC(=O)c1c(N)n(CC2CCCO2)c2nc(ccc2c1=O)C#CC(C)(C)O

InChI Key InChIKey=VVPYQNGWCJEVDW-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98612   

TargetVascular endothelial growth factor receptor 3(Human)
Sanofi

US Patent

LigandBDBM98612(2-amino-7-(3-hydroxy-3-methyl-but-1-ynyl)-N-methyl...)Copy SMILESCopy InChI

Affinity DataIC50: 40nMT: 2°CAssay Description:Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/29/2013
Entry Details
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