BDBM99194 US8501708, 14::US8501708, 15

SMILES OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCCC3OCc3ccccc3)ncnc12

InChI Key InChIKey=JNBXZKKJHPLGEA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 99194   

TargetAdenosine receptor A1(Rabbit)
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM99194(US8501708, 15 | US8501708, 14)
Affinity DataKi:  29nMAssay Description:The compounds were studied in binding assays to determine selectivity and potency to A1, A2a and A3 adenosine receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2013
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Rabbit)
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM99194(US8501708, 15 | US8501708, 14)
Affinity DataKi:  53.1nMAssay Description:The compounds were studied in binding assays to determine selectivity and potency to A1, A2a and A3 adenosine receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2013
Entry Details
Go to US Patent

TargetAdenosine receptor A3(Rabbit)
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM99194(US8501708, 15 | US8501708, 14)
Affinity DataKi:  2.55E+3nMAssay Description:The compounds were studied in binding assays to determine selectivity and potency to A1, A2a and A3 adenosine receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2013
Entry Details
Go to US Patent

TargetAdenosine receptor A2(Rabbit)
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM99194(US8501708, 15 | US8501708, 14)
Affinity DataKi:  3.74E+3nMAssay Description:The compounds were studied in binding assays to determine selectivity and potency to A1, A2a and A3 adenosine receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2013
Entry Details
Go to US Patent

TargetAdenosine receptor A2(Rabbit)
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM99194(US8501708, 15 | US8501708, 14)
Affinity DataKi:  2.54E+4nMAssay Description:The compounds were studied in binding assays to determine selectivity and potency to A1, A2a and A3 adenosine receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2013
Entry Details
Go to US Patent

TargetAdenosine receptor A3(Rabbit)
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM99194(US8501708, 15 | US8501708, 14)
Affinity DataKi: >1.00E+5nMAssay Description:The compounds were studied in binding assays to determine selectivity and potency to A1, A2a and A3 adenosine receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2013
Entry Details
Go to US Patent