BDBM27495 6-chloro-2,3-dimethylimidazo[1,2-a]pyridin-8-ol::BYK20370

SMILES Cc1nc2c(O)cc(Cl)cn2c1C

InChI Key InChIKey=JJTUIIUDUVKJDA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27495   

TargetPoly [ADP-ribose] polymerase 1(Human)
University of Konstanz

LigandPNGBDBM27495(6-chloro-2,3-dimethylimidazo[1,2-a]pyridin-8-ol | ...)
Affinity DataIC50: 398nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
University of Konstanz

LigandPNGBDBM27495(6-chloro-2,3-dimethylimidazo[1,2-a]pyridin-8-ol | ...)
Affinity DataIC50: 1.95E+3nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed