BDBM50513995 BCX-4430::Bcx4430::Galidesivir

SMILES c1c(c2c([nH]1)c(ncn2)N)[C@H]3[C@@H]([C@@H]([C@H](N3)CO)O)O

InChI Key InChIKey=AMFDITJFBUXZQN-UHFFFAOYSA-N

Data  8 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50513995   

TargetGenome polyprotein(ZIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Malaysian P 6-740 infected in human Huh-7 cells assessed as antiviral activity by neutral dy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Ugandan MR-766 infected in human RD cells assessed as antiviral activity by neutral dye base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC-59 infected in human RD cells assessed as antiviral activity by neutral dye based col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Malaysian P 6-740 infected in African green monkey Vero cells assessed as antiviral activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC-59 infected in African green monkey Vero cells assessed as antiviral activity by neut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC-59 infected in human HuH7 cells assessed as antiviral activity by neutral dye based c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Ugandan MR-766 infected in African green monkey Vero cells assessed as antiviral activity by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Ugandan MR-766 infected in human Huh-7 cells assessed as antiviral activity by neutral dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed