BDBM50284267 Boropinal

SMILES [#6]-[#8]-c1cc(\[#6]=[#6]\[#6]=O)ccc1-[#8]-[#6]\[#6]=[#6](\[#6])-[#6]

InChI Key InChIKey=AYALWLJUFVEBGS-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50284267   

LigandPNGBDBM50284267(Boropinal)
Affinity DataEC50:  9.80E+3nMAssay Description:Activation of human TRPA1 expressed in HEK293 cells assessed as increase in calcium level by fluo-4 dye based plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50284267(Boropinal)
Affinity DataEC50:  9.80E+3nMAssay Description:Activation of human TRPA1 expressed in HEK293 cells assessed as increase in calcium level by fluo-4 dye based plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50284267(Boropinal)
Affinity DataKi:  786nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cell lysates after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2020
Entry Details Article
PubMed