BDBM50136024 3-(9-isopropoxymethyl-5-oxo-6,7,12,13-tetrahydro-5H-indeno[2,1-a]pyrrolo[4,3-c]carbazol-12-yl)propyl 2-dimethylaminoacetate::CEP-7055::CHEMBL346631

SMILES CC(C)OCc1ccc2n(CCCOC(=O)CN(C)C)c3c4Cc5ccccc5-c4c4C(=O)NCc4c3c2c1

InChI Key InChIKey=UHEBDUAFKQHUBV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136024   

LigandPNGBDBM50136024(CEP-7055 | 3-(9-isopropoxymethyl-5-oxo-6,7,12,13-t...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136024(CEP-7055 | 3-(9-isopropoxymethyl-5-oxo-6,7,12,13-t...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50136024(CEP-7055 | 3-(9-isopropoxymethyl-5-oxo-6,7,12,13-t...)
Affinity DataIC50: 16nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed