BDBM50032982 (3-Amino-propyl)-butyl-phosphinic acid::3-aminopropyl(butyl)phosphinic acid::CGP36742::CHEMBL112797

SMILES CCCCP(O)(=O)CCCN

InChI Key InChIKey=ONNMDRQRSGKZCN-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50032982   

LigandPNGBDBM50032982(CGP36742 | 3-aminopropyl(butyl)phosphinic acid | C...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of binding of [3H]CGP-27492 to gamma-aminobutyric acid type B receptor of rat cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50032982(CGP36742 | 3-aminopropyl(butyl)phosphinic acid | C...)
Affinity DataIC50: 6.20E+4nMAssay Description:Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50032982(CGP36742 | 3-aminopropyl(butyl)phosphinic acid | C...)
Affinity DataIC50: 5.08E+5nMAssay Description:Antagonist activity at human recombinant GABAA alpha1beta2gamma2L receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50032982(CGP36742 | 3-aminopropyl(butyl)phosphinic acid | C...)
Affinity DataIC50: 3.80E+4nMAssay Description:Antagonist activity at human recombinant GABAb 1b/2 receptor expressed in Xenopus laevis oocytes co-expressing GIRK1/4 assessed as inhibition of GABA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50032982(CGP36742 | 3-aminopropyl(butyl)phosphinic acid | C...)
Affinity DataIC50: 6.20E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50032982(CGP36742 | 3-aminopropyl(butyl)phosphinic acid | C...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3(Human)
University of Sydney

Curated by PDSP Ki Database
LigandPNGBDBM50032982(CGP36742 | 3-aminopropyl(butyl)phosphinic acid | C...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details
PubMed