BDBM50473083 CHEMBL342285::CI-1044

SMILES Nc1cc2CCN3c2c(c1)C(=N[C@@H](NC(=O)c1cccnc1)C3=O)c1ccccc1

InChI Key InChIKey=XGXOSJSGDNPEEF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50473083   

LigandPNGBDBM50473083(CI-1044 | CHEMBL342285)
Affinity DataIC50: 270nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50473083(CI-1044 | CHEMBL342285)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of [3H]rolipram binding to Wistar rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50473083(CI-1044 | CHEMBL342285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1/5 isozyme (PDE1/5) mixture isolated from the guinea pig trachea.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50473083(CI-1044 | CHEMBL342285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of phosphodiesterase 3 (PDE3) isolated from the dog aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed