BDBM50285522 1-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-1H-benzoimidazole-5-carbonitrile::CHEMBL75642::CP-161242

SMILES CN1CCC[C@@H]1Cc1c[nH]c2ccc(cc12)-n1cnc2cc(ccc12)C#N

InChI Key InChIKey=KVKYGVOAHGNAKZ-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50285522   

Target5-hydroxytryptamine receptor 1D(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50285522(CP-161242 | 1-[3-((R)-1-Methyl-pyrrolidin-2-ylmeth...)
Affinity DataEC50:  0.0420nMAssay Description:Compound was tested for the inhibition of forskolin-stimulated adenylate cyclase at 5-hydroxytryptamine 1D receptor in guinea pig substantia nigraMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285522(CP-161242 | 1-[3-((R)-1-Methyl-pyrrolidin-2-ylmeth...)
Affinity DataIC50: 1.30nMAssay Description:Tested in vitro for receptor binding affinity to 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]5-HT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50285522(CP-161242 | 1-[3-((R)-1-Methyl-pyrrolidin-2-ylmeth...)
Affinity DataIC50: 20nMAssay Description:Tested in vitro for receptor binding affinity to 5-hydroxytryptamine 1A receptor in rat cortex using [3H]OH-DPAT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285522(CP-161242 | 1-[3-((R)-1-Methyl-pyrrolidin-2-ylmeth...)
Affinity DataEC50:  26nMAssay Description:Compound was tested for the inhibition of forskolin-stimulated adenylate cyclase at 5-hydroxytryptamine 1A receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article