BDBM50006048 2-methoxy-3-(octadecylcarbamoyloxy)propyl 2-(thiazol-3-ium-3-yl)ethyl phosphate::3-{2-[(2-Methoxy-3-octadecylcarbamoyloxy-propoxy)-phosphonooxy-methoxy]-ethyl}-thiazol-3-ium::3-{2-[Hydroxy-(2-methoxy-3-octadecylcarbamoyloxy-propoxy)-phosphoryloxy]-ethyl}-thiazol-3-ium::3-{2-[Hydroxy-(2-methoxy-3-octadecylcarbamoyloxy-propoxy)-phosphoryloxy]-ethyl}-thiazol-3-ium(CV-3988)::CHEMBL295212::CV-3988::Octadecyl-carbamic acid 3-[hydroxy-(2-thiazol-3-yl-ethoxy)-phosphorylo xy]-2-methoxy-propyl ester(CV-3988)

SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COP([O-])(=O)OCC[n+]1ccsc1)OC

InChI Key InChIKey=NMHKTASGTFXJPL-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50006048   

TargetPlatelet-activating factor receptor(Guinea pig)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50006048(CV-3988 | 2-methoxy-3-(octadecylcarbamoyloxy)propy...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50006048(CV-3988 | 2-methoxy-3-(octadecylcarbamoyloxy)propy...)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of PAF-induced platelet aggregation in rabbit platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006048(CV-3988 | 2-methoxy-3-(octadecylcarbamoyloxy)propy...)
Affinity DataIC50: 600nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006048(CV-3988 | 2-methoxy-3-(octadecylcarbamoyloxy)propy...)
Affinity DataKi:  575nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006048(CV-3988 | 2-methoxy-3-(octadecylcarbamoyloxy)propy...)
Affinity DataKi:  686nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details
PubMed