BDBM91950 Chk1_82

SMILES COc1ccc(Nc2[nH]nc-3c2Cc2ccccc-32)cc1

InChI Key InChIKey=DSOLTOIQZRMXJS-UHFFFAOYSA-N

Data  1 KI  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 91950   

TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL

LigandBDBM91950(Chk1_82)Copy SMILESCopy InChI

Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human HeLa cells expressing HRE-Luc after 12 hrs by luciferase reporter gene assa...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
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TargetSerine/threonine-protein kinase Chk1 [2-280](Human)
D3R/Abbott

LigandBDBM91950(Chk1_82)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:33P-Radiometric_Method1More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/10/2017
Entry Details
Copy BDB DOID3R

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TargetSerine/threonine-protein kinase Chk1(Human)
Csar

LigandBDBM91950(Chk1_82)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Abbott Kinase Enzymatics_CHK1/289 CDC25c - IC50(uM) (IC50)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/7/2012
Entry Details PubMed
Copy reaction URL