BDBM50387480 CHEMBL467894::Cyanines, 5

SMILES CCN1\C(=C\C=C\C2=[N+](CC)c3ccccc3C2(C)C)C(C)(C)c2ccccc12

InChI Key InChIKey=PUIDNHIQNRMZGS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50387480   

TargetIsoform Tau-F of Microtubule-associated protein tau(Human)
The Ohio State University

LigandPNGBDBM50387480(CHEMBL467894 | Cyanines, 5)
Affinity DataIC50: 980nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50387480(CHEMBL467894 | Cyanines, 5)
Affinity DataIC50: 2.84E+5nMAssay Description:Inhibition of His-tagged PRMT1 expressed in Escherichia coli BL21(DE3) cells using [14C]-S-adenosyl-L-methionine and histone H4 peptide after 8 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed