BDBM50000855 6-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl)quinolin-2(1H)-one::6-[3-Fluoro-5-(4-methoxy-tetrahydro-pyran-4-yl)-phenoxymethyl]-1H-quinolin-2-one::CHEMBL87747::D-2138::ZD-2138

SMILES COC1(CCOCC1)c1cc(F)cc(OCc2ccc3[nH]c(=O)ccc3c2)c1

InChI Key InChIKey=NLNLBHXPBULZQF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000855   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000855(6-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50: 600nMAssay Description:In vitro inhibition of leukotriene B4 synthesis in human whole blood by inhibiting 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed