BDBM50087702 (2-Chloro-4,6-dimethyl-phenyl)-[1-(2-methoxy-1-methoxymethyl-ethyl)-6-methyl-1H-[1,2,3]triazolo[4,5-c]pyridin-4-yl]-amine; compound with methanesulfonic acid::CHEMBL44169::DMP-695

SMILES COCC(COC)n1nnc2c(Nc3c(C)cc(C)cc3Cl)nc(C)cc12

InChI Key InChIKey=ZQDGDIAWYBGDRC-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087702   

TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087702(DMP-695 | (2-Chloro-4,6-dimethyl-phenyl)-[1-(2-met...)
Affinity DataKi:  3.30nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087702(DMP-695 | (2-Chloro-4,6-dimethyl-phenyl)-[1-(2-met...)
Affinity DataIC50: 75nMAssay Description:Inhibition of corticotropin releasing factor receptor mediated increase in cAMP level using HEK293 cells expressing h-CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087702(DMP-695 | (2-Chloro-4,6-dimethyl-phenyl)-[1-(2-met...)
Affinity DataIC50: 79nMAssay Description:Inhibition of corticotropin releasing factor receptor mediated increase in cAMP level using rat cortical homogenates in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed