BDBM50002051 (+/-)-(2RS)-2-[(4RS)-2,2-Diphenyl-1,3-dioxolan-4-yl]piperidine::(+/-)-(2RS)-2-[(4SR)-2,2-diphenyl-1,3-dioxolan-4-yl]piperidine::(Dexoxadrol)2-(2,2-Diphenyl-[1,3]dioxolan-4-yl)-piperidine::CHEMBL26479::Dexoxadrol

SMILES C1OC(OC1C1CCCCN1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=HGKAMARNFGKMLC-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50002051   

LigandPNGBDBM50002051(CHEMBL26479 | Dexoxadrol | (+/-)-(2RS)-2-[(4RS)-2,...)
Affinity DataKi:  23nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Westf£Lischen Wilhems-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50002051(CHEMBL26479 | Dexoxadrol | (+/-)-(2RS)-2-[(4RS)-2,...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 opioid receptor from guinea pig brain cortex after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50002051(CHEMBL26479 | Dexoxadrol | (+/-)-(2RS)-2-[(4RS)-2,...)
Affinity DataKi:  41nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50002051(CHEMBL26479 | Dexoxadrol | (+/-)-(2RS)-2-[(4RS)-2,...)
Affinity DataKi:  46nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
LigandPNGBDBM50002051(CHEMBL26479 | Dexoxadrol | (+/-)-(2RS)-2-[(4RS)-2,...)
Affinity DataKi:  141nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50002051(CHEMBL26479 | Dexoxadrol | (+/-)-(2RS)-2-[(4RS)-2,...)
Affinity DataKi:  569nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institut FüR Pharmazeutische Und Medizinische Chemie Der WestfäLischen Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50002051(CHEMBL26479 | Dexoxadrol | (+/-)-(2RS)-2-[(4RS)-2,...)
Affinity DataKi: >800nMAssay Description:Binding affinity to sigma1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50002051(CHEMBL26479 | Dexoxadrol | (+/-)-(2RS)-2-[(4RS)-2,...)
Affinity DataKi:  1.05E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
LigandPNGBDBM50002051(CHEMBL26479 | Dexoxadrol | (+/-)-(2RS)-2-[(4RS)-2,...)
Affinity DataKi:  1.88E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50002051(CHEMBL26479 | Dexoxadrol | (+/-)-(2RS)-2-[(4RS)-2,...)
Affinity DataKi:  2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed