BDBM50024156 2-(1-{[1-(2-Hydroxy-1-isobutyl-5-methyl-4-{2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexylcarbamoyl)-2-(3H-imidazol-4-yl)-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-pyrrolidine-1-carboxylic acid tert-butyl ester::CHEMBL303323::Ditekiren

SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C)C(C)C)C(=O)NCc1ccccn1

InChI Key InChIKey=SASWSEQJAITMKS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50024156   

TargetPepsin A(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50024156(2-(1-{[1-(2-Hydroxy-1-isobutyl-5-methyl-4-{2-methy...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of porcine pepsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024156(2-(1-{[1-(2-Hydroxy-1-isobutyl-5-methyl-4-{2-methy...)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50024156(2-(1-{[1-(2-Hydroxy-1-isobutyl-5-methyl-4-{2-methy...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of bovine cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed