BDBM392715 Example 9::US10301291, Compound 11c

SMILES N#CCc1cnc(-c2ccc3ccccc3n2)n1-c1ccnc(NC2CCCCC2)n1

InChI Key InChIKey=YAYHNPYFBMMMLU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392715   

TargetMitogen-activated protein kinase 10(Human)
Samjin Pharmaceutical

US Patent
LigandPNGBDBM392715(Example 9 | US10301291, Compound 11c)
Affinity DataIC50: 100nMAssay Description:First of all, after a substrate was inserted into a prepared base reaction buffer solution (20 mM Hepes (pH 75), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase 10(Human)
Samjin Pharmaceutical

US Patent
LigandPNGBDBM392715(Example 9 | US10301291, Compound 11c)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed