BDBM50523931 Cyclofenil::F 6066::ICI 48213::Neoclym::Rehibin

SMILES [#6]-[#6](=O)-[#8]-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#6]-[#6]-[#6]-1)\c1ccc(-[#8]-[#6](-[#6])=O)cc1

InChI Key InChIKey=FLHNUTJWMZXJLN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523931   

TargetEstrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50523931(Cyclofenil | F 6066 | ICI 48213 | Neoclym | Rehibi...)
Affinity DataEC50:  26nMAssay Description:Selective estrogen receptor down-regulator activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as induction of ERalph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50523931(Cyclofenil | F 6066 | ICI 48213 | Neoclym | Rehibi...)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as reduction in E2-induced ER-alpha-mediated transcrip...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed