BDBM102424 FIDAS-3::Fluorinated N,N-Dialkylaminostilbenes 3

SMILES CN(C)c1ccc(\C=C\c2c(F)cccc2F)cc1

InChI Key InChIKey=YBJDCOLXJYDHOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 102424   

TargetS-adenosylmethionine synthase(Escherichia coli (strain SMS-3-5 / SECEC))
University of Kentucky

LigandPNGBDBM102424(Fluorinated N,N-Dialkylaminostilbenes 3 | FIDAS-3)
Affinity DataIC50: 4.90E+3nMAssay Description:MAT2A was incubated with FIDAS agents at RT for 20 min andthen mixed with L-methionine and ATP in 0.5 mL of reaction buffer.Cold deionized water (2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM102424(Fluorinated N,N-Dialkylaminostilbenes 3 | FIDAS-3)
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of human ERG over-expressed in HEK293 cell membrane by [3H]dofetilide binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM102424(Fluorinated N,N-Dialkylaminostilbenes 3 | FIDAS-3)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human recombinant His-tagged MAT2A expressed in Escherichia coli expression system assessed as S-adenosyl methionine production using L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed