BDBM102425 FIDAS-5::Fluorinated N,N-Dialkylaminostilbenes 5

SMILES CNc1ccc(\C=C\c2c(F)cccc2Cl)cc1

InChI Key InChIKey=KXVXICBOMOGFMH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 102425   

TargetS-adenosylmethionine synthase(Escherichia coli (strain SMS-3-5 / SECEC))
University of Kentucky

LigandPNGBDBM102425(Fluorinated N,N-Dialkylaminostilbenes 5 | FIDAS-5)
Affinity DataIC50: 2.10E+3nMAssay Description:MAT2A was incubated with FIDAS agents at RT for 20 min andthen mixed with L-methionine and ATP in 0.5 mL of reaction buffer.Cold deionized water (2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM102425(Fluorinated N,N-Dialkylaminostilbenes 5 | FIDAS-5)
Affinity DataIC50: 4.98E+4nMAssay Description:Inhibition of human ERG over-expressed in HEK293 cell membrane by [3H]dofetilide binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM102425(Fluorinated N,N-Dialkylaminostilbenes 5 | FIDAS-5)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant His-tagged MAT2A expressed in Escherichia coli expression system assessed as S-adenosyl methionine production using L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed