BDBM50311743 CHEMBL487992::GARTANIN

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2oc3c(-[#8])ccc(-[#8])c3c(=O)c2c1-[#8]

InChI Key InChIKey=ASNYTZXTAIIVRE-UHFFFAOYSA-N

Data  1 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50311743   

TargetNuclear factor NF-kappa-B p105 subunit(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of Clostridium perfringens neuraminidase by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNEDD8-conjugating enzyme Ubc12(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of Ubc12 (unknown origin)-neddylation incubated for 30 mins in presence of ATP by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataEC50:  1.79E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataKi:  3.60E+3nMAssay Description:Competitive inhibition of Clostridium perfringens neuraminidase by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed