BDBM50172447 (E)-N-[2-(4-Ethyl-piperazin-1-yl)-4-methyl-quinolin-6-yl]-3-(4-methoxy-phenyl)-acrylamide::CHEMBL196573::GNF-Pf-1550

SMILES CCN1CCN(CC1)c1cc(C)c2cc(NC(=O)\C=C\c3ccc(OC)cc3)ccc2n1

InChI Key InChIKey=BYSCWUNLAIWJED-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172447   

TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172447((E)-N-[2-(4-Ethyl-piperazin-1-yl)-4-methyl-quinoli...)
Affinity DataIC50: 16nMAssay Description:Displacement of 150p M [125I]MCH from human MCH1R expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50172447((E)-N-[2-(4-Ethyl-piperazin-1-yl)-4-methyl-quinoli...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3R expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details Article
PubMed