BDBM27499 1,11b-dihydro-[2H]benzopyrano[4,3,2-de]isoquinolin-3-one::8-oxa-15-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-2(7),3,5,9(17),10,12-hexaen-14-one::GPI-6150

SMILES O=C1NCC2c3ccccc3Oc3cccc1c23

InChI Key InChIKey=ZRUZRVJWCFFMMF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27499   

TargetPoly [ADP-ribose] polymerase 1(Human)
University of Konstanz

LigandPNGBDBM27499(8-oxa-15-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]hep...)
Affinity DataIC50: 83nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
University of Konstanz

LigandPNGBDBM27499(8-oxa-15-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]hep...)
Affinity DataIC50: 186nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed