BDBM50623161 GSK-1059615::GSK-615::GSK1059615::GSK615::Gsk-1059615

SMILES O=C1NC(=O)\C(S1)=C\c1ccc2nccc(-c3ccncc3)c2c1

InChI Key InChIKey=QDITZBLZQQZVEE-UHFFFAOYSA-N

Data  8 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50623161   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50623161(Gsk-1059615 | GSK-615 | GSK1059615 | GSK615 | GSK-...)Copy SMILESCopy InChI

Affinity DataIC50: 0.400nMAssay Description:Inhibition of P13Kalpha (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50623161(Gsk-1059615 | GSK-615 | GSK1059615 | GSK615 | GSK-...)Copy SMILESCopy InChI

Affinity DataIC50: 0.600nMAssay Description:Inhibition of P13Kbeta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50623161(Gsk-1059615 | GSK-615 | GSK1059615 | GSK615 | GSK-...)Copy SMILESCopy InChI

Affinity DataIC50: 5nMAssay Description:Inhibition of P13Kgamma (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50623161(Gsk-1059615 | GSK-615 | GSK1059615 | GSK615 | GSK-...)Copy SMILESCopy InChI

Affinity DataIC50: 2nMAssay Description:Inhibition of P13Kdelta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50623161(Gsk-1059615 | GSK-615 | GSK1059615 | GSK615 | GSK-...)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50623161(Gsk-1059615 | GSK-615 | GSK1059615 | GSK615 | GSK-...)Copy SMILESCopy InChI

Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50623161(Gsk-1059615 | GSK-615 | GSK1059615 | GSK615 | GSK-...)Copy SMILESCopy InChI

Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50623161(Gsk-1059615 | GSK-615 | GSK1059615 | GSK615 | GSK-...)Copy SMILESCopy InChI

Affinity DataIC50: 2nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL