BDBM81818 CAS_1794::CHEMBL1909810::HMA::NSC_1794

SMILES NC(=N)NC(=O)c1nc(Cl)c(nc1N)N1CCCCCC1

InChI Key InChIKey=RQQJJXVETXFINY-UHFFFAOYSA-N

Data  34 KI  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 52 hits for monomerid = 81818   

TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 0.190nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlasma kallikrein(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma kallikrein using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 270nMAssay Description:Displacement of [3H]ZM-241,385 from human N-terminal FLAG-tagged adenosine A2A receptor W246A 6.48 mutant expressed in HEK293 cell membrane by microb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 5.10E+3nMAssay Description:Displacement of [3H]ZM-241,385 from human N-terminal FLAG-tagged adenosine A2A receptor expressed in HEK293 cell membrane by microbeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details Article
PubMed
TargetTrypsin(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of trypsin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of activated protein C (unknown origin) using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of factor 10a (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of factor 11a (unknown origin) using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of tPA (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human kidney uPA using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of thrombin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPlasminogen(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of plasmin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of recombinant human ERG expressed in CHO cells incubated for 12 mins by whole cell voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
Tokushima University

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 171nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Tokushima University

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 1.51E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 3.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human Nav1.5alpha expressed in HEK293 cells incubated for 10 mins by voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  54nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  61nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  410nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  1.36E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  2.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  3.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  3.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  4.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  4.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  5.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  5.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Pig)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  6.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  7.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi:  9.31E+3nMAssay Description:Inhibition of mouse uPA using Z-Gly-Gly-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetPro-thyrotropin-releasing hormone(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetProtachykinin-1(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetGlycine amidinotransferase, mitochondrial(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel gamma-1 subunit(Human)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Mouse)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine 1D receptor(Bovine)
Center For Bio-Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
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