BDBM50034747 (Z)-6-[(2S,4S,5R)-2-(2-Chloro-phenyl)-4-(2-hydroxy-phenyl)-[1,3]dioxan-5-yl]-hex-4-enoic acid::CHEMBL30024::ICI-192605

SMILES OC(=O)CC\C=C/C[C@@H]1CO[C@@H](O[C@@H]1c1ccccc1O)c1ccccc1Cl

InChI Key InChIKey=WHUIENZXNGAHQI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50034747   

TargetThromboxane-A synthase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50034747(ICI-192605 | (Z)-6-[(2S,4S,5R)-2-(2-Chloro-phenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human microsomal thromboxane synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50034747(ICI-192605 | (Z)-6-[(2S,4S,5R)-2-(2-Chloro-phenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro Inhibition of thromboxane synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50034747(ICI-192605 | (Z)-6-[(2S,4S,5R)-2-(2-Chloro-phenyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for thromboxane TXA2 synthase inhibitory activity using human plateletMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article